Domains within Homo sapiens protein E7ERS3_HUMAN (E7ERS3)

Zinc finger CCCH domain-containing protein 18

Alternative representations: 1 /

Protein length977 aa
Source databaseUniProt
Identifiers E7ERS3_HUMAN, E7ERS3, ENSP00000416951.2, ENSP00000416951, H3BRH3_HUMAN, H3BRH3, B3KRL4_HUMAN, B3KRL4
Source gene ENSG00000158545
Alternative splicing ZCH18_HUMAN, E7ERS3_HUMAN, H3BPD0_HUMAN, H3BP01_HUMAN, H3BRN6_HUMAN, ENSP00000456241.1

Predicted functional partners

E7ERS3_HUMAN is shown as ZC3H18 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ZC3H18

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000416951 in eggNOG.

OGTaxonomic classDescription
6YJQKAll organisms (root)type I keratin, acidic,endoglucanase [EC:3.2.1.4],type II keratin, basic
KOG0266Eukaryota (superkingdom)type I keratin, acidic,endoglucanase [EC:3.2.1.4],type II keratin, basic
HT85EMetazoa (kingdom)nuclear protein NHN1
94WTRChordata (phylum)nuclear protein NHN1
5QUZDSarcopterygii (superclass)nuclear protein NHN1
8ZIX4Mammalia (class)nuclear protein NHN1
4RMJZEuarchontoglires (superorder)nuclear protein NHN1
50109Primates (order)nuclear protein NHN1
98I1QHaplorrhini (suborder)nuclear protein NHN1
BV66USimiiformes (infraorder)nuclear protein NHN1
9EHHSCatarrhini (parvorder)nuclear protein NHN1
7I6ANOpisthokonta (clade)nuclear protein NHN1
H5ICXBilateria (clade)nuclear protein NHN1
9FZ3UVertebrata (clade)nuclear protein NHN1
FWYHPHominoidea (superfamily)nuclear protein NHN1
5N1UFHominidae (family)nuclear protein NHN1
5XUZ1Homininae (subfamily)nuclear protein NHN1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: