Domains within Danio rerio protein ENSDARP00000145630.1

Alternative representations: 1 /

Protein length129 aa
Source databaseEnsembl
Identifiers ENSDARP00000145630.1, ENSDARP00000145630
Source gene ENSDARG00000037262
Alternative splicing ENSDARP00000145630.1, E9QFU2_DANRE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSDARP00000145630.1 is shown as cdkn2a/b in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for cdkn2a/b

Protein ENSDARP00000145630.1 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04350TGF-beta signaling pathway
map05166Human T-cell leukemia virus 1 infection
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K10999CESAcellulose synthase A [EC:2.4.1.12]
K04685CDKN2B, P15, INK4Bcyclin-dependent kinase inhibitor 2B
K06867K06867uncharacterized protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000145630 in eggNOG.

OGTaxonomic classDescription
LCOG0666All organisms (root)uncharacterized protein,Mce-associated membrane protein,cellulose synthase A [EC:2.4.1.12]
9IERUOtomorpha (cohort)cyclin-dependent kinase inhibitor 2B
KOG0504Eukaryota (superkingdom)cellulose synthase A [EC:2.4.1.12],beta-mannan synthase [EC:2.4.1.32],uncharacterized protein
HWBKXMetazoa (kingdom)cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinase inhibitor 2A
94NWFChordata (phylum)cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinase inhibitor 2A
FYB5FActinopterygii (superclass)cyclin-dependent kinase inhibitor 2B
8NNPSNeopterygii (subclass)cyclin-dependent kinase inhibitor 2B
9FJ3AVertebrata (clade)cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinase inhibitor 2A
7JFW5Opisthokonta (clade)cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinase inhibitor 2A
H5RIUBilateria (clade)cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinase inhibitor 2A
BEWS0Cyprinidae (family)cyclin-dependent kinase inhibitor 2B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: