Domains within Macaca mulatta protein ENSMMUP00000014698.3

Alternative representations: 1 /

Protein length390 aa
Source databaseEnsembl
Identifiers ENSMMUP00000014698.3, ENSMMUP00000014698
Source gene ENSMMUG00000011216
Alternative splicing ENSMMUP00000014698.3, ENSMMUP00000014702.2, A0A1D5RAW5_MACMU

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSMMUP00000014698.3 is shown as MEIS1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for MEIS1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 6 PTMs annotated in this protein:

PTMCount
Phosphorylation4
SUMOylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein MEIS1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000272369 in eggNOG.

OGTaxonomic classDescription
LKOG0773All organisms (root)iroquois-class homeodomain protein IRX,homeobox protein PKNOX,homeobox protein Mohawk
KOG0773Eukaryota (superkingdom)iroquois-class homeodomain protein IRX,homeobox protein PKNOX,homeobox protein Mohawk
HVWU4Metazoa (kingdom)homeobox protein Meis2,homeobox protein Meis1,homeobox protein homothorax
93T79Chordata (phylum)homeobox protein Meis2,homeobox protein Meis1
5QKA2Sarcopterygii (superclass)homeobox protein Meis2,homeobox protein Meis1
8YXWMMammalia (class)homeobox protein Meis2,homeobox protein Meis1
4RH3ZEuarchontoglires (superorder)homeobox protein Meis1,homeobox protein Meis2
4ZTB2Primates (order)homeobox protein Meis1
98Q21Haplorrhini (suborder)homeobox protein Meis1
BV3MXSimiiformes (infraorder)homeobox protein Meis1
9EUBPCatarrhini (parvorder)homeobox protein Meis1
7GG9YOpisthokonta (clade)homeobox protein Meis2,homeobox protein Meis1,homeobox protein homothorax
H595KBilateria (clade)homeobox protein homothorax,homeobox protein Meis2,homeobox protein Meis1
9G3DHVertebrata (clade)homeobox protein Meis2,homeobox protein Meis1
FX654Hominoidea (superfamily)homeobox protein Meis1
5NDNJHominidae (family)homeobox protein Meis1
5XVPRHomininae (subfamily)homeobox protein Meis1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: