Domains within Mus musculus protein ENSMUSP00000076666.5

Alternative representations: 1 /

Protein length1430 aa
Source databaseEnsembl
Identifiers ENSMUSP00000076666.5, ENSMUSP00000076666, ENSMUSP00000040825.7, ENSMUSP00000040825
Source gene ENSMUSG00000021559
Alternative splicing DAPK1_MOUSE, ENSMUSP00000076666.5, A0A286YDD8_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

ENSMUSP00000076666.5 is shown as Dapk1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Dapk1

Protein ENSMUSP00000076666.5 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05219Bladder cancer
map04020Calcium signaling pathway
map05145Toxoplasmosis

KEGG orthologous groups

KONameDescription
K13412CPKcalcium-dependent protein kinase [EC:2.7.11.1]
K08803DAPKdeath-associated protein kinase [EC:2.7.11.1]
K08794CAMK1calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 10 PTMs annotated in this protein:

PTMCount
Phosphorylation8
Ubiquitination1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Dapk1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000076666 in eggNOG.

OGTaxonomic classDescription
LKOG0032All organisms (root)calcium-dependent protein kinase [EC:2.7.11.1],calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17],death-associated protein kinase [EC:2.7.11.1]
KOG0032Eukaryota (superkingdom)calcium-dependent protein kinase [EC:2.7.11.1],calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17],death-associated protein kinase [EC:2.7.11.1]
HTTQFMetazoa (kingdom)death-associated protein kinase [EC:2.7.11.1],calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
93ZW1Chordata (phylum)death-associated protein kinase [EC:2.7.11.1]
5QFIXSarcopterygii (superclass)death-associated protein kinase [EC:2.7.11.1]
8Z5WQMammalia (class)death-associated protein kinase [EC:2.7.11.1]
4RM2FEuarchontoglires (superorder)death-associated protein kinase [EC:2.7.11.1]
AHXKARodentia (order)death-associated protein kinase [EC:2.7.11.1]
8DAWYMyomorpha (suborder)death-associated protein kinase [EC:2.7.11.1]
9FY3XVertebrata (clade)death-associated protein kinase [EC:2.7.11.1]
7JKKDOpisthokonta (clade)calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17],death-associated protein kinase [EC:2.7.11.1],CaM kinase-like vesicle-associated [EC:2.7.11.-]
H5QMABilateria (clade)death-associated protein kinase [EC:2.7.11.1],calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
CQ05SMuridae (family)death-associated protein kinase [EC:2.7.11.1]
AE9D3Murinae (subfamily)death-associated protein kinase [EC:2.7.11.1]
5PFKZMus (genus)death-associated protein kinase [EC:2.7.11.1]
HE3FBMus (subgenus)death-associated protein kinase [EC:2.7.11.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: