Domains within Homo sapiens protein ENSP00000297579.5

Alternative representations: 1 /

Protein length597 aa
Source databaseEnsembl
Identifiers ENSP00000297579.5, ENSP00000297579, ENSP00000477526.1, ENSP00000477526
Source gene ENSG00000164934
Alternative splicing ENSP00000297579.5, E5RHM4_HUMAN, ENSP00000484168.1, DCA13_HUMAN, B3KME9_HUMAN, Q9NV06-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000297579.5 is shown as DCAF13 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DCAF13

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 7 PTMs annotated in this protein:

PTMCount
Ubiquitination4
Acetylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein DCAF13.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000297579 in eggNOG.

OGTaxonomic classDescription
LKOG0268All organisms (root)DDB1- and CUL4-associated factor 13
KOG0268Eukaryota (superkingdom)DDB1- and CUL4-associated factor 13
HSXKFMetazoa (kingdom)DDB1- and CUL4-associated factor 13
945YWChordata (phylum)DDB1- and CUL4-associated factor 13
5QZJCSarcopterygii (superclass)DDB1- and CUL4-associated factor 13
8Z6HTMammalia (class)DDB1- and CUL4-associated factor 13
4RFS4Euarchontoglires (superorder)DDB1- and CUL4-associated factor 13
4ZMDWPrimates (order)DDB1- and CUL4-associated factor 13
98ADPHaplorrhini (suborder)DDB1- and CUL4-associated factor 13
BV8H0Simiiformes (infraorder)DDB1- and CUL4-associated factor 13
9F1FFCatarrhini (parvorder)DDB1- and CUL4-associated factor 13
7MGPVOpisthokonta (clade)DDB1- and CUL4-associated factor 13
H3ZUJBilateria (clade)DDB1- and CUL4-associated factor 13
9FBINVertebrata (clade)DDB1- and CUL4-associated factor 13
FX1JWHominoidea (superfamily)DDB1- and CUL4-associated factor 13
5MYGIHominidae (family)DDB1- and CUL4-associated factor 13
5Y496Homininae (subfamily)DDB1- and CUL4-associated factor 13

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: