Domains within Homo sapiens protein ENSP00000344149.4

Alternative representations: 1 /

Protein length261 aa
Source databaseEnsembl
Identifiers ENSP00000344149.4, ENSP00000344149
Source gene ENSG00000188529
Alternative splicing ENSP00000342913.5, ENSP00000388991.3, ENSP00000419813.2, R4GMP8_HUMAN, ENSP00000363576.5, Q5JRI1_HUMAN, ENSP00000344149.4, SRS10_HUMAN, Q6IQ42_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000344149.4 is shown as SRSF10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SRSF10

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 26 PTMs annotated in this protein:

PTMCount
Phosphorylation26

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSMMUG00000013784.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9544.ENSMMUP00000051639 in eggNOG.

OGTaxonomic classDescription
LKOG0118All organisms (root)heterogeneous nuclear ribonucleoprotein A1/A3,transformer-2 protein,serine/arginine-rich splicing factor 10
KOG0118Eukaryota (superkingdom)heterogeneous nuclear ribonucleoprotein A1/A3,transformer-2 protein,serine/arginine-rich splicing factor 10
HTA6CMetazoa (kingdom)serine/arginine-rich splicing factor 10,serine/arginine-rich splicing factor 12,La-related protein 7
949GQChordata (phylum)serine/arginine-rich splicing factor 12,serine/arginine-rich splicing factor 10,cilia- and flagella-associated protein 69
5QYZQSarcopterygii (superclass)serine/arginine-rich splicing factor 10
8Z4IHMammalia (class)serine/arginine-rich splicing factor 10
4RRH0Euarchontoglires (superorder)serine/arginine-rich splicing factor 10
500VMPrimates (order)serine/arginine-rich splicing factor 10
9883NHaplorrhini (suborder)serine/arginine-rich splicing factor 10
BVIZ1Simiiformes (infraorder)serine/arginine-rich splicing factor 10
9EN60Catarrhini (parvorder)serine/arginine-rich splicing factor 10
H3VWTBilateria (clade)serine/arginine-rich splicing factor 10,serine/arginine-rich splicing factor 12,La-related protein 7
9GSCCVertebrata (clade)serine/arginine-rich splicing factor 10,serine/arginine-rich splicing factor 12
7GT12Opisthokonta (clade)serine/arginine-rich splicing factor 10,serine/arginine-rich splicing factor 12,La-related protein 7
6HXNGCercopithecidae (family)serine/arginine-rich splicing factor 10
BR444Cercopithecinae (subfamily)serine/arginine-rich splicing factor 10
531F7Macaca (genus)serine/arginine-rich splicing factor 10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: