Domains within Homo sapiens protein ENSP00000346328.7

Alternative representations: 1 /

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ENSP00000346328.7 is shown as GNAS in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for GNAS

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9755.ENSPCTP00005025929 in eggNOG.

OGTaxonomic classDescription
LKOG0099All organisms (root)guanine nucleotide-binding protein G(s) subunit alpha,guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein subunit alpha, other
KOG0099Eukaryota (superkingdom)guanine nucleotide-binding protein G(s) subunit alpha,guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein subunit alpha, other
HW6RWMetazoa (kingdom)guanine nucleotide-binding protein G(s) subunit alpha,guanine nucleotide-binding protein G(olf) subunit alpha
94RRQChordata (phylum)guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein G(s) subunit alpha
5QGJ7Sarcopterygii (superclass)guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein G(s) subunit alpha
8Z1TVMammalia (class)guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein G(s) subunit alpha
BQM7QLaurasiatheria (superorder)guanine nucleotide-binding protein G(s) subunit alpha
AX5SUArtiodactyla (order)guanine nucleotide-binding protein G(s) subunit alpha
BJQYJCetacea (infraorder)guanine nucleotide-binding protein G(s) subunit alpha
87A6GOdontoceti (parvorder)guanine nucleotide-binding protein G(s) subunit alpha
7IKP3Opisthokonta (clade)guanine nucleotide-binding protein G(s) subunit alpha,guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein subunit alpha, other
9GP1ZVertebrata (clade)guanine nucleotide-binding protein G(olf) subunit alpha,guanine nucleotide-binding protein G(s) subunit alpha
H5Y5SBilateria (clade)guanine nucleotide-binding protein G(s) subunit alpha,guanine nucleotide-binding protein G(olf) subunit alpha

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: