Domains within Homo sapiens protein ENSP00000370088.3

Alternative representations: 1 /

Protein length205 aa
Source databaseEnsembl
Identifiers ENSP00000370088.3, ENSP00000370088
Source gene ENSG00000125363
Alternative splicing AMELX_HUMAN, ENSP00000370088.3, ENSP00000335312.5

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

ENSP00000370088.3 is shown as AMELX in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for AMELX

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AMELX.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9598.ENSPTRP00000057175 in eggNOG.

OGTaxonomic classDescription
6Y54YAll organisms (root)amelogenin
5K8P8Eukaryota (superkingdom)amelogenin
HVD8TMetazoa (kingdom)amelogenin
940VVChordata (phylum)amelogenin
5RABHSarcopterygii (superclass)amelogenin
8YUY7Mammalia (class)amelogenin
4RH8XEuarchontoglires (superorder)amelogenin
4ZN8FPrimates (order)amelogenin
98GFUHaplorrhini (suborder)amelogenin
BUY1JSimiiformes (infraorder)amelogenin
9ERXBCatarrhini (parvorder)amelogenin
7K57UOpisthokonta (clade)amelogenin
9FXZNVertebrata (clade)amelogenin
H6769Bilateria (clade)amelogenin
FXF28Hominoidea (superfamily)amelogenin
5N3GQHominidae (family)amelogenin
5Y87DHomininae (subfamily)Amelogenin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: