Domains within Homo sapiens protein ENSP00000379503.3

Alternative representations: 1 /

Protein length562 aa
Source databaseEnsembl
Identifiers ENSP00000379503.3, ENSP00000379503
Source gene ENSG00000164951
Alternative splicing PDP1_HUMAN, ENSP00000430931.1, ENSP00000430366.1, ENSP00000428433.1, ENSP00000430655.1, ENSP00000429492.1, ENSP00000379503.3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000379503.3 is shown as PDP1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PDP1

Protein ENSP00000379503.3 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04075Plant hormone signal transduction

KEGG orthologous groups

KONameDescription
K20074prpC, phpPPPM family protein phosphatase [EC:3.1.3.16]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000379503 in eggNOG.

OGTaxonomic classDescription
LCOG0631All organisms (root)PPM family protein phosphatase [EC:3.1.3.16],protein phosphatase 1L [EC:3.1.3.16],pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
KOG0700Eukaryota (superkingdom)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
HSZVKMetazoa (kingdom)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
94PVUChordata (phylum)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
5QU75Sarcopterygii (superclass)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
8YWCFMammalia (class)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
4R6ANEuarchontoglires (superorder)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
4ZK2TPrimates (order)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
988R2Haplorrhini (suborder)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
BV0M9Simiiformes (infraorder)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
9EH0ACatarrhini (parvorder)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
H51Y4Bilateria (clade)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
9FI8QVertebrata (clade)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
7JG9EOpisthokonta (clade)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
FX73THominoidea (superfamily)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
5NEF5Hominidae (family)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]
5Y81DHomininae (subfamily)pyruvate dehydrogenase phosphatase [EC:3.1.3.43]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: