Domains within Homo sapiens protein ENSP00000381070.2

Alternative representations: 1 /

Protein length435 aa
Source databaseEnsembl
Identifiers ENSP00000381070.2, ENSP00000381070
Source gene ENSG00000076984
Alternative splicing ENSP00000381068.3, ENSP00000381070.2, MP2K7_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000381070.2 is shown as MAP2K7 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for MAP2K7

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9601.ENSPPYP00000010648 in eggNOG.

OGTaxonomic classDescription
LKOG0983All organisms (root)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2],C-C motif chemokine 25
KOG0983Eukaryota (superkingdom)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2],C-C motif chemokine 25
HVJUAMetazoa (kingdom)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2],C-C motif chemokine 25
94UYBChordata (phylum)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],C-C motif chemokine 25
5R1K0Sarcopterygii (superclass)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],C-C motif chemokine 25
8YXI8Mammalia (class)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],C-C motif chemokine 25
4RJ8QEuarchontoglires (superorder)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],C-C motif chemokine 25
4ZZY6Primates (order)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
98QX7Haplorrhini (suborder)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
BV63FSimiiformes (infraorder)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
9ETDTCatarrhini (parvorder)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
7N29BOpisthokonta (clade)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2],C-C motif chemokine 25
H735WBilateria (clade)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2],C-C motif chemokine 25
9G22JVertebrata (clade)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2],C-C motif chemokine 25
FX95GHominoidea (superfamily)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
5NCM8Hominidae (family)mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: