Domains within Homo sapiens protein ENSP00000402243.2

Alternative representations: 1 /

Protein length319 aa
Source databaseEnsembl
Identifiers ENSP00000402243.2, ENSP00000402243
Source gene ENSG00000160199
Alternative splicing PKNX1_HUMAN, H0YM69_HUMAN, ENSP00000402243.2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000402243.2 is shown as PKNOX1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PKNOX1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 60711.ENSCSAP00000004303 in eggNOG.

OGTaxonomic classDescription
LKOG0773All organisms (root)iroquois-class homeodomain protein IRX,homeobox protein PKNOX,homeobox protein Mohawk
KOG0773Eukaryota (superkingdom)iroquois-class homeodomain protein IRX,homeobox protein PKNOX,homeobox protein Mohawk
HUZ9VMetazoa (kingdom)homeobox protein PKNOX,homeobox protein TGIF1,homeobox protein TGIF2
93MU9Chordata (phylum)homeobox protein PKNOX
5R5C9Sarcopterygii (superclass)homeobox protein PKNOX
8Z7HEMammalia (class)homeobox protein PKNOX
4R7BCEuarchontoglires (superorder)homeobox protein PKNOX
4ZYDCPrimates (order)homeobox protein PKNOX
98EMNHaplorrhini (suborder)homeobox protein PKNOX
BV376Simiiformes (infraorder)homeobox protein PKNOX
9F1J7Catarrhini (parvorder)homeobox protein PKNOX
9GKSZVertebrata (clade)homeobox protein PKNOX
7KV3FOpisthokonta (clade)homeobox protein PKNOX,homeobox protein TGIF1,homeobox protein TGIF2
H3GCABilateria (clade)homeobox protein PKNOX,homeobox protein TGIF1,homeobox protein TGIF2
6IB90Cercopithecidae (family)homeobox protein PKNOX
BRIIFCercopithecinae (subfamily)homeobox protein PKNOX

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: