Domains within Homo sapiens protein ENSP00000409800.1

Alternative representations: 1 /

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ENSP00000409800.1 is shown as ENSDORP00000021076 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ENSDORP00000021076

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 37548.ENSCAPP00000013032 in eggNOG.

OGTaxonomic classDescription
LKOG1029All organisms (root)intersectin,Rho guanine nucleotide exchange factor 3/8,actin cytoskeleton-regulatory complex protein PAN1
LKOG4305All organisms (root)Rho guanine nucleotide exchange factor 3/8,intersectin,RHO1 GDP-GTP exchange protein 1/2
KOG1029Eukaryota (superkingdom)intersectin,Rho guanine nucleotide exchange factor 3/8,actin cytoskeleton-regulatory complex protein PAN1
KOG4305Eukaryota (superkingdom)Rho guanine nucleotide exchange factor 3/8,intersectin,RHO1 GDP-GTP exchange protein 1/2
HTBKPMetazoa (kingdom)intersectin
94KDVChordata (phylum)intersectin
5R9QRSarcopterygii (superclass)intersectin
8ZJGRMammalia (class)intersectin
4RG1TEuarchontoglires (superorder)intersectin
AIC8FRodentia (order)intersectin
EVJ2BHystricomorpha (suborder)SH3_9,EF-hand_4,SH3_1
9GPJWVertebrata (clade)intersectin
7GPU3Opisthokonta (clade)intersectin,actin cytoskeleton-regulatory complex protein PAN1
H5PAEBilateria (clade)intersectin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: