Domains within Homo sapiens protein ENSP00000441890.1

Alternative representations: 1 /

Protein length209 aa
Source databaseEnsembl
Identifiers ENSP00000441890.1, ENSP00000441890
Source gene ENSG00000087494
Alternative splicing PTHR_HUMAN, ENSP00000441890.1, Q53XY9_HUMAN, ENSP00000444519.1, F5H485_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

ENSP00000441890.1 is shown as PTHLH in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PTHLH

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 61622.ENSRROP00000023012 in eggNOG.

OGTaxonomic classDescription
6Z6SPAll organisms (root)parathyroid hormone-related hormone
5EU6GEukaryota (superkingdom)parathyroid hormone-related hormone
HV2B1Metazoa (kingdom)parathyroid hormone-related hormone
93W1RChordata (phylum)parathyroid hormone-related hormone
5QF9TSarcopterygii (superclass)parathyroid hormone-related hormone
8ZM4BMammalia (class)parathyroid hormone-related hormone
4R3IZEuarchontoglires (superorder)parathyroid hormone-related hormone
4ZX2QPrimates (order)parathyroid hormone-related hormone
98Q49Haplorrhini (suborder)parathyroid hormone-related hormone
BV7RFSimiiformes (infraorder)parathyroid hormone-related hormone
9EZJ1Catarrhini (parvorder)parathyroid hormone-related hormone
7HRM4Opisthokonta (clade)parathyroid hormone-related hormone
H56X1Bilateria (clade)parathyroid hormone-related hormone
9G70KVertebrata (clade)parathyroid hormone-related hormone
6IE96Cercopithecidae (family)parathyroid hormone-related hormone
EG7HWColobinae (subfamily)parathyroid hormone-related hormone

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: