Domains within Homo sapiens protein ENSP00000454264.1

Alternative representations: 1 /

Protein length639 aa
Source databaseEnsembl
Identifiers ENSP00000454264.1, ENSP00000454264
Source gene ENSG00000013374
Alternative splicing H3BM14_HUMAN, ENSP00000454264.1, F8WDB6_HUMAN, NUB1_HUMAN, ENSP00000420086.1, F8WDL9_HUMAN, H7C5N1_HUMAN, H7C5E1_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

ENSP00000454264.1 is shown as NUB1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NUB1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000454264 in eggNOG.

OGTaxonomic classDescription
LKOG2561All organisms (root)UBA,Ubiquitin_5,ubiquitin
KOG2561Eukaryota (superkingdom)UBA,Ubiquitin_5,ubiquitin
HSKWVMetazoa (kingdom)UBA,Ubiquitin_5,DUF4682
93EC1Chordata (phylum)Ubiquitin_5,UBA,DUF4682
5QR93Sarcopterygii (superclass)Ubiquitin_5,UBA,DUF4682
8Z05NMammalia (class)Ubiquitin_5,UBA
4RGSWEuarchontoglires (superorder)Ubiquitin_5,UBA
4ZNZIPrimates (order)Ubiquitin_5,UBA
98KWAHaplorrhini (suborder)Ubiquitin_5,UBA
BUZ6WSimiiformes (infraorder)Ubiquitin_5,UBA
9EQ65Catarrhini (parvorder)Ubiquitin_5,UBA
9GIWDVertebrata (clade)Ubiquitin_5,UBA,DUF4682
7HJMHOpisthokonta (clade)UBA,Ubiquitin_5,DUF4682
H5BCYBilateria (clade)UBA,Ubiquitin_5,DUF4682
FWXQ4Hominoidea (superfamily)Ubiquitin_5,UBA
5NB90Hominidae (family)Ubiquitin_5,UBA
5XYBHHomininae (subfamily)Ubiquitin_5,UBA

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: