Domains within Homo sapiens protein ENSP00000468952.1

Alternative representations: 1 /

Protein length166 aa
Source databaseEnsembl
Identifiers ENSP00000468952.1, ENSP00000468952, ENSP00000385077.1, ENSP00000385077, ENSP00000471006.1, ENSP00000471006
Source gene ENSG00000104852
Alternative splicing ENSP00000468952.1, ENSP00000470023.1, RU17_HUMAN, ENSP00000221448.5, M0QX04_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000468952.1 is shown as SNRNP70-2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SNRNP70-2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9925.ENSCHIP00000019571 in eggNOG.

OGTaxonomic classDescription
LCOG0724All organisms (root)serine/arginine-rich splicing factor 4/5/6,serine/arginine-rich splicing factor 1,cleavage stimulation factor subunit 2
KOG0113Eukaryota (superkingdom)U1 small nuclear ribonucleoprotein 70kDa,U11/U12 small nuclear ribonucleoprotein 35 kDa protein,[histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
HUY3WMetazoa (kingdom)U1 small nuclear ribonucleoprotein 70kDa,U11/U12 small nuclear ribonucleoprotein 35 kDa protein,[histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
93JV2Chordata (phylum)U11/U12 small nuclear ribonucleoprotein 35 kDa protein,U1 small nuclear ribonucleoprotein 70kDa,[histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
5QBTXSarcopterygii (superclass)U1 small nuclear ribonucleoprotein 70kDa
8YZBYMammalia (class)U1 small nuclear ribonucleoprotein 70kDa
BQJQYLaurasiatheria (superorder)U1 small nuclear ribonucleoprotein 70kDa
AX3G7Artiodactyla (order)U1 small nuclear ribonucleoprotein 70kDa
B624FPecora (infraorder)U1 small nuclear ribonucleoprotein 70kDa
9G6FYVertebrata (clade)U11/U12 small nuclear ribonucleoprotein 35 kDa protein,U1 small nuclear ribonucleoprotein 70kDa,[histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
H3YXXBilateria (clade)U1 small nuclear ribonucleoprotein 70kDa,U11/U12 small nuclear ribonucleoprotein 35 kDa protein,[histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
7KKEPOpisthokonta (clade)U1 small nuclear ribonucleoprotein 70kDa,U11/U12 small nuclear ribonucleoprotein 35 kDa protein,[histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
7PCTTBovidae (family)U1 small nuclear ribonucleoprotein 70kDa

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: