Domains within Rattus norvegicus protein ENSRNOP00000046059.1

Alternative representations: 1 /

Protein length825 aa
Source databaseEnsembl
Identifiers ENSRNOP00000046059.1, ENSRNOP00000046059
Source gene ENSRNOG00000018674
Alternative splicing ENSRNOP00000046059.1, NTRK3_RAT, ENSRNOP00000049463.1, Q68G04_RAT

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

ENSRNOP00000046059.1 is shown as Ntrk3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ntrk3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 26 PTMs annotated in this protein:

PTMCount
Phosphorylation19
N-linked glycosylation4
Ubiquitination3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Ntrk3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000037909 in eggNOG.

OGTaxonomic classDescription
LCOG0478All organisms (root)serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-],RAC serine/threonine-protein kinase [EC:2.7.11.1],pto-interacting protein 1 [EC:2.7.11.1]
KOG1026Eukaryota (superkingdom)receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1],muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1],PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
HVF3JMetazoa (kingdom)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
93MTFChordata (phylum)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
5QNRVSarcopterygii (superclass)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
8YWAYMammalia (class)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
4R4UEEuarchontoglires (superorder)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
AI4GHRodentia (order)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
8DCYHMyomorpha (suborder)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
9G88XVertebrata (clade)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
H3JHWBilateria (clade)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
7MRHUOpisthokonta (clade)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
CQ84JMuridae (family)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
AE4XBMurinae (subfamily)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
5PUPUMus (genus)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
HE7Y4Mus (subgenus)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: