Domains within Homo sapiens protein F1D8N5_HUMAN (F1D8N5)

Androgen nuclear receptor variant 2

Alternative representations: 1 /

Protein length388 aa
Source databaseUniProt
Identifiers F1D8N5_HUMAN, F1D8N5, ENSP00000379358.2, ENSP00000379358, A0A2I3T1P9_PANTR, A0A2I3T1P9, Q5RFF5_PONAB, Q5RFF5, P10275-2
Source gene ENSG00000169083
Alternative splicing ANDR_HUMAN, P10275-3, ENSP00000425199.1, F1D8N5_HUMAN, A0A087WZ66_HUMAN, A0A087WUX9_HUMAN, A0A087X1B6_HUMAN, F5GZG9_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Metazoa

Predicted functional partners

F1D8N5_HUMAN is shown as DKFZp468G2216 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DKFZp468G2216

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9601.ENSPPYP00000022865 in eggNOG.

OGTaxonomic classDescription
LKOG3575All organisms (root)estrogen-related receptor gamma,nuclear receptor subfamily 2 group E member 3,retinoid X receptor alpha
KOG3575Eukaryota (superkingdom)estrogen-related receptor gamma,nuclear receptor subfamily 2 group E member 3,retinoid X receptor alpha
HTWGTMetazoa (kingdom)androgen receptor
93V0WChordata (phylum)androgen receptor
5R3U3Sarcopterygii (superclass)androgen receptor
8YYMBMammalia (class)androgen receptor
4RCIVEuarchontoglires (superorder)androgen receptor
502DUPrimates (order)androgen receptor
986ZRHaplorrhini (suborder)androgen receptor
BVGQYSimiiformes (infraorder)androgen receptor
9EKGUCatarrhini (parvorder)androgen receptor
H5ZYFBilateria (clade)androgen receptor
7JF4GOpisthokonta (clade)androgen receptor
9FH1TVertebrata (clade)androgen receptor
FWZZJHominoidea (superfamily)androgen receptor
5N2CUHominidae (family)androgen receptor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: