Domains within Homo sapiens protein F1T0C9_HUMAN (F1T0C9)

Homeobox protein OTX2

Alternative representations: 1 /

Protein length35 aa
Source databaseUniProt
Identifiers F1T0C9_HUMAN, F1T0C9, ENSP00000474486.1, ENSP00000474486, ENSP00000450468.1, ENSP00000450468, A0A2I3RE13_PANTR, A0A2I3RE13, A0A2J8WL53_PONAB, A0A2J8WL53, A0A1D5QJ97_MACMU, A0A1D5QJ97, A0A2I2ZWD9_GORGO, A0A2I2ZWD9, A0A2K5TL54_MACFA, A0A2K5TL54, A0A2K6LMM8_RHIBE, A0A2K6LMM8, A0A2K6E0S2_MACNE, A0A2K6E0S2, A0A2K5NK56_CERAT, A0A2K5NK56, A0A2K6RCU4_RHIRO, A0A2K6RCU4, A0A2I3MQZ9_PAPAN, A0A2I3MQZ9, A0A2K5E8Z8_AOTNA, A0A2K5E8Z8, A0A2K6TLB2_SAIBB, A0A2K6TLB2, A0A2K5HVB8_COLAP, A0A2K5HVB8, A0A2K5RJ14_CEBCA, A0A2K5RJ14, A0A2K5YKR1_MANLE, A0A2K5YKR1
Source gene ENSG00000165588
Alternative splicing F1T0D1_HUMAN, OTX2_HUMAN, F1T0C9_HUMAN, ENSP00000451357.1, ENSP00000451272.1

Predicted functional partners

F1T0C9_HUMAN is shown as OTX2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for OTX2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9483.ENSCJAP00000057088 in eggNOG.

OGTaxonomic classDescription
LKOG2251All organisms (root)homeobox protein OTX2,homeobox protein OTX1,cone-rod homeobox protein
KOG2251Eukaryota (superkingdom)homeobox protein OTX2,homeobox protein OTX1,cone-rod homeobox protein
HV258Metazoa (kingdom)homeobox protein OTX2,cone-rod homeobox protein,homeobox protein OTX1
93FY9Chordata (phylum)homeobox protein OTX2,cone-rod homeobox protein,homeobox protein OTX1
5RC4NSarcopterygii (superclass)homeobox protein OTX2,cone-rod homeobox protein
8ZJZQMammalia (class)homeobox protein OTX2
4R8A4Euarchontoglires (superorder)homeobox protein OTX2
4ZTV7Primates (order)homeobox protein OTX2
98AANHaplorrhini (suborder)homeobox protein OTX2
BUYS4Simiiformes (infraorder)homeobox protein OTX2
53H8QPlatyrrhini (parvorder)homeobox protein OTX2
7P3MROpisthokonta (clade)homeobox protein OTX2,cone-rod homeobox protein,homeobox protein OTX1
9FE0QVertebrata (clade)homeobox protein OTX2,cone-rod homeobox protein
H3KH3Bilateria (clade)homeobox protein OTX2,cone-rod homeobox protein,homeobox protein OTX1
9Z942Cebidae (family)homeobox protein OTX2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: