Domains within Mus musculus protein FLNA_MOUSE (Q8BTM8)

Filamin-A

Alternative representations: 1 /

Protein length2647 aa
Source databaseUniProt
Identifiers FLNA_MOUSE, Q8BTM8, ENSMUSP00000033699.6, ENSMUSP00000033699, B7FAV0, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2, Q4FZG4_MOUSE, Q4FZG4, Q3U7N9_MOUSE, Q3U7N9
Source gene ENSMUSG00000031328
Alternative splicing F6XC15_MOUSE, B7FAU9_MOUSE, FLNA_MOUSE, B7FAV1_MOUSE, J3JS91_MOUSE, F7AVL7_MOUSE, F6Z2C0_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 205 PTMs annotated in this protein:

PTMCount
Phosphorylation126
Ubiquitination30
Nitrosylation21
Acetylation21
Caspase cleavage aspartic acid3
Methylation1
SUMOylation1
Proteolytic cleavage1
Oxidation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Flna.

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: