Domains within Homo sapiens protein FLNB_HUMAN (O75369)

Filamin-B

Alternative representations: 1 /

Protein length2602 aa
Source databaseUniProt
Identifiers FLNB_HUMAN, O75369, ENSP00000295956.4, ENSP00000295956, B2ZZ83, B2ZZ84, B2ZZ85, C9JKE6, C9JMC4, Q13706, Q59EC2, Q60FE7, Q6MZJ1, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q8WXT3, Q9NRB5, Q9NT26, Q9UEV9
Source gene ENSG00000136068
Alternative splicing O75369-8, FLNB_HUMAN, O75369-2, O75369-9, E7EN95_HUMAN, H7C5L4_HUMAN, ENSP00000419954.1, A0A0A0MT44_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 198 PTMs annotated in this protein:

PTMCount
Phosphorylation132
Ubiquitination25
Acetylation23
Nitrosylation13
Caspase cleavage aspartic acid3
Methylation1
SUMOylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein DKFZp686A1668.

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: