Domains within Pan troglodytes protein H2Q908_PANTR (H2Q908)

BRF1, RNA polymerase III transcription initiation factor subunit

Alternative representations: 1 /

Protein length658 aa
Source databaseUniProt
Identifiers H2Q908_PANTR, H2Q908, ENSPTRP00000011599.6, ENSPTRP00000011599
Source gene ENSPTRG00000006786
Alternative splicing A0A2I3TMV7_PANTR, A0A2I3TGP0_PANTR, A0A2I3TXP7_PANTR, H2Q908_PANTR, A0A2I3S9Z4_PANTR

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

H2Q908_PANTR is shown as BRF1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BRF1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9598.ENSPTRP00000011599 in eggNOG.

OGTaxonomic classDescription
LKOG1598All organisms (root)transcription factor IIIB 50 kDa subunit,transcription factor IIIB 90 kDa subunit,transcription factor MYB, plant
KOG1598Eukaryota (superkingdom)transcription factor IIIB 50 kDa subunit,transcription factor IIIB 90 kDa subunit,transcription factor MYB, plant
HTFRCMetazoa (kingdom)transcription factor IIIB 90 kDa subunit
93XJMChordata (phylum)transcription factor IIIB 90 kDa subunit
5R3N1Sarcopterygii (superclass)transcription factor IIIB 90 kDa subunit
8Z08UMammalia (class)transcription factor IIIB 90 kDa subunit
4RR4DEuarchontoglires (superorder)transcription factor IIIB 90 kDa subunit
500Z9Primates (order)transcription factor IIIB 90 kDa subunit
98HF4Haplorrhini (suborder)transcription factor IIIB 90 kDa subunit
BVHT3Simiiformes (infraorder)transcription factor IIIB 90 kDa subunit
9ERN0Catarrhini (parvorder)transcription factor IIIB 90 kDa subunit
H3YC1Bilateria (clade)transcription factor IIIB 90 kDa subunit
7NF0IOpisthokonta (clade)transcription factor IIIB 90 kDa subunit
9FRYJVertebrata (clade)transcription factor IIIB 90 kDa subunit
FXED2Hominoidea (superfamily)transcription factor IIIB 90 kDa subunit
5N0JZHominidae (family)transcription factor IIIB 90 kDa subunit
5XWW6Homininae (subfamily)transcription factor IIIB 90 kDa subunit

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: