Domains within Homo sapiens protein H3BPR2_HUMAN (H3BPR2)

Nucleoside diphosphate kinase

Alternative representations: 1 /

Protein length85 aa
Source databaseUniProt
Identifiers H3BPR2_HUMAN, H3BPR2, ENSP00000455435.1, ENSP00000455435, A0A2J8R976_PONAB, A0A2J8R976, A0A2J8J7T5_PANTR, A0A2J8J7T5, A0A2K6KUZ6_RHIBE, A0A2K6KUZ6, A0A2K5HF01_COLAP, A0A2K5HF01, A0A2K6KUY0_RHIBE, A0A2K6KUY0, A0A2K5ZLF0_MANLE, A0A2K5ZLF0
Source gene ENSG00000103024
Alternative splicing NDK3_HUMAN, H3BRA8_HUMAN, H3BPD9_HUMAN, H3BPR2_HUMAN, H3BMQ7_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

H3BPR2_HUMAN is shown as NME3 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NME3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 336983.ENSCANP00000002923 in eggNOG.

OGTaxonomic classDescription
LCOG0105All organisms (root)nucleoside-diphosphate kinase [EC:2.7.4.6],nucleoside diphosphate kinase homolog 5,small subunit ribosomal protein S34
KOG0888Eukaryota (superkingdom)nucleoside-diphosphate kinase [EC:2.7.4.6],nucleoside diphosphate kinase homolog 5,small subunit ribosomal protein S34
HVF7NMetazoa (kingdom)nucleoside-diphosphate kinase [EC:2.7.4.6],small subunit ribosomal protein S34
94A6AChordata (phylum)nucleoside-diphosphate kinase [EC:2.7.4.6],small subunit ribosomal protein S34
5R7N1Sarcopterygii (superclass)nucleoside-diphosphate kinase [EC:2.7.4.6]
8YWFDMammalia (class)nucleoside-diphosphate kinase [EC:2.7.4.6]
4RKZWEuarchontoglires (superorder)nucleoside-diphosphate kinase [EC:2.7.4.6]
4ZV3FPrimates (order)nucleoside-diphosphate kinase [EC:2.7.4.6]
98ASNHaplorrhini (suborder)nucleoside-diphosphate kinase [EC:2.7.4.6]
BV7PISimiiformes (infraorder)nucleoside-diphosphate kinase [EC:2.7.4.6]
9EMP2Catarrhini (parvorder)nucleoside-diphosphate kinase [EC:2.7.4.6]
H6I57Bilateria (clade)nucleoside-diphosphate kinase [EC:2.7.4.6],small subunit ribosomal protein S34
7K489Opisthokonta (clade)nucleoside-diphosphate kinase [EC:2.7.4.6],small subunit ribosomal protein S34,NADPH-dependent reductase
9GQI8Vertebrata (clade)nucleoside-diphosphate kinase [EC:2.7.4.6],small subunit ribosomal protein S34
6I8R8Cercopithecidae (family)nucleoside-diphosphate kinase [EC:2.7.4.6]
EGDFJColobinae (subfamily)nucleoside-diphosphate kinase [EC:2.7.4.6]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: