Domains within Mus musculus protein H7BX26_MOUSE (H7BX26)

Centrosomal protein of 170 kDa

Alternative representations: 1 /

Protein length1578 aa
Source databaseUniProt
Identifiers H7BX26_MOUSE, H7BX26, ENSMUSP00000141769.1, ENSMUSP00000141769, ENSMUSP00000059562.6, ENSMUSP00000059562
Source gene ENSMUSG00000057335
Alternative splicing A0A0A6YVZ3_MOUSE, H7BX26_MOUSE, CE170_MOUSE, A0A0A6YXK7_MOUSE, A0A0A6YXR9_MOUSE, A0A0A6YX99_MOUSE, A0A0A6YXT4_MOUSE, Q6A065-2, A0A0A6YWV9_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

H7BX26_MOUSE is shown as Cep170 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cep170

Protein H7BX26_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04974Protein digestion and absorption

KEGG orthologous groups

KONameDescription
K19721COL5AScollagen type V/XI/XXIV/XXVII, alpha

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000141769 in eggNOG.

OGTaxonomic classDescription
LKOG3544All organisms (root)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
KOG3544Eukaryota (superkingdom)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
HU2VSMetazoa (kingdom)centrosomal protein CEP170,inverted formin-2
94B08Chordata (phylum)centrosomal protein CEP170,inverted formin-2
5QGW7Sarcopterygii (superclass)centrosomal protein CEP170
8ZFCVMammalia (class)centrosomal protein CEP170
4RC86Euarchontoglires (superorder)centrosomal protein CEP170
9FHAMVertebrata (clade)centrosomal protein CEP170,inverted formin-2
H6QJ7Bilateria (clade)centrosomal protein CEP170,inverted formin-2
7M0ZPOpisthokonta (clade)centrosomal protein CEP170,serine/arginine repetitive matrix protein 2,inverted formin-2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: