Domains within Drosophila melanogaster protein H9XVN1_DROME (H9XVN1)

Rho GTPase activating protein at 102A, isoform D

Alternative representations: 1 /

Protein length1256 aa
Source databaseUniProt
Identifiers H9XVN1_DROME, H9XVN1, FBPP0300897
Source gene FBgn0259216
Alternative splicing H9XVN1_DROME, Q2PDM2_DROME, Q9V4C2_DROME, L0MPN2_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

H9XVN1_DROME is shown as RhoGAP102A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RhoGAP102A

Protein H9XVN1_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04011MAPK signaling pathway - yeast

KEGG orthologous groups

KONameDescription
K20631ARHGAP6Rho GTPase-activating protein 6

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0300897 in eggNOG.

OGTaxonomic classDescription
EJ66HEndopterygota (cohort)Rho GTPase-activating protein 6
FE23Qmelanogaster subgroup (species subgroup)Rho GTPase-activating protein 6
FUXJ9melanogaster group (species group)Rho GTPase-activating protein 6
LKOG2710All organisms (root)Rho GTPase-activating protein 6,Rho GTPase-activating protein 11,GTPase-activating protein SAC7
KOG2710Eukaryota (superkingdom)Rho GTPase-activating protein 6,Rho GTPase-activating protein 11,GTPase-activating protein SAC7
HV582Metazoa (kingdom)Rho GTPase-activating protein 6
HIFWAArthropoda (phylum)Rho GTPase-activating protein 6
85I2XHexapoda (subphylum)Rho GTPase-activating protein 6
AHT8TNeoptera (infraclass)Rho GTPase-activating protein 6
ANWS9Diptera (order)Rho GTPase-activating protein 6
H4JT5Bilateria (clade)Rho GTPase-activating protein 6
7KF38Opisthokonta (clade)Rho GTPase-activating protein 6
EGYEADrosophila (genus)Rho GTPase-activating protein 6
50ES6Sophophora (subgenus)Rho GTPase-activating protein 6

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: