Domains within Macaca mulatta protein HXC10_MACMU (A2D635)

Homeobox protein Hox-C10

Alternative representations: 1 /

Protein length342 aa
Source databaseUniProt
Identifiers HXC10_MACMU, A2D635, ENSMMUP00000001242.3, ENSMMUP00000001242, HXC10_MACNE, A2T6F8, G7PHV9_MACFA, G7PHV9, F6R702_MACMU, F6R702
Source gene ENSMMUG00000000925
Alternative splicing HXC10_MACMU, A0A1D5R1D2_MACMU

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

HXC10_MACMU is shown as HOXC10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HOXC10

Protein HXC10_MACMU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05202Transcriptional misregulation in cancer

KEGG orthologous groups

KONameDescription
K09296HOX_11homeobox protein HoxC/D11
K09298HOX_13homeobox protein HoxA/B/C/D13

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9544.ENSMMUP00000001242 in eggNOG.

OGTaxonomic classDescription
LKOG0487All organisms (root)homeobox protein HoxA/B/C/D13,homeobox protein HoxB/C/D9,homeobox protein HoxC/D12
KOG0487Eukaryota (superkingdom)homeobox protein HoxA/B/C/D13,homeobox protein HoxB/C/D9,homeobox protein HoxC/D12
HSPJ5Metazoa (kingdom)homeobox protein HoxC/D11,homeobox protein Hox-A11,homeobox protein Hox-A9
94DZPChordata (phylum)homrobox protein Hox-C10,homeobox protein HoxB/C/D8
5QKIFSarcopterygii (superclass)homrobox protein Hox-C10,homeobox protein HoxB/C/D8
8ZAMFMammalia (class)homrobox protein Hox-C10,homeobox protein HoxB/C/D8
4RIPTEuarchontoglires (superorder)homeobox protein HoxB/C/D8,homrobox protein Hox-C10
4ZVXGPrimates (order)homeobox protein HoxB/C/D8,homrobox protein Hox-C10
986T7Haplorrhini (suborder)homeobox protein HoxB/C/D8,homrobox protein Hox-C10
BV4A6Simiiformes (infraorder)homeobox protein HoxB/C/D8,homrobox protein Hox-C10
9EGAACatarrhini (parvorder)homrobox protein Hox-C10
7HN7HOpisthokonta (clade)homeobox protein HoxC/D11,homeobox protein Hox-A11,homeobox protein Hox-A9
9G13TVertebrata (clade)homrobox protein Hox-C10,homeobox protein HoxB/C/D8
H3CEVBilateria (clade)homrobox protein Hox-C10,homeobox protein HoxB/C/D8
6IAAMCercopithecidae (family)homrobox protein Hox-C10
BRDJHCercopithecinae (subfamily)homrobox protein Hox-C10
531HBMacaca (genus)homrobox protein Hox-C10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: