Domains within Homo sapiens protein I3L2H7_HUMAN (I3L2H7)

Ubiquitin-conjugating enzyme E2 G1

Alternative representations: 1 /

Protein length99 aa
Source databaseUniProt
Identifiers I3L2H7_HUMAN, I3L2H7, ENSP00000459691.1, ENSP00000459691, A0A212DA06_CEREH, A0A212DA06, A0A2D4K2L9_9SAUR, A0A2D4K2L9, A0A2J8SPH6_PONAB, A0A2J8SPH6, A0A2J8KQV9_PANTR, A0A2J8KQV9, A0A2K6TDY5_SAIBB, A0A2K6TDY5, A0A2K6GIC8_PROCO, A0A2K6GIC8, F6Z696_ORNAN, F6Z696, A0A2I3GDC2_NOMLE, A0A2I3GDC2, D6RES1_MOUSE, D6RES1, A0A1A6GU34_NEOLE, A0A1A6GU34, A0A286XT43_CAVPO, A0A286XT43, I3N9M2_ICTTR, I3N9M2, K7EPR7_HUMAN, K7EPR7, A0A2J8SPH5_PONAB, A0A2J8SPH5, A0A2J8KQZ0_PANTR, A0A2J8KQZ0, D2I1D8_AILME, D2I1D8, W5QCH9_SHEEP, W5QCH9, L8HZA1_9CETA, L8HZA1, H0Z0K6_TAEGU, H0Z0K6, G1MUV5_MELGA, G1MUV5, A0A226PFL9_COLVI, A0A226PFL9
Source gene ENSG00000132388
Alternative splicing UB2G1_HUMAN, I3L2H7_HUMAN, ENSP00000458253.1, ENSP00000459847.1, ENSP00000467502.1, ENSP00000459485.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

I3L2H7_HUMAN is shown as ENSPCOP00000025995 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ENSPCOP00000025995

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 379532.ENSPCOP00000025995 in eggNOG.

OGTaxonomic classDescription
LCOG5078All organisms (root)ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24],ubiquitin-conjugating enzyme E2 I
KOG0425Eukaryota (superkingdom)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23],U4/U6.U5 tri-snRNP component SNU23
HVYXGMetazoa (kingdom)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
93UFKChordata (phylum)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
5RD2FSarcopterygii (superclass)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
8ZG3JMammalia (class)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
4R7GUEuarchontoglires (superorder)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
504Y8Primates (order)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
GN0SEStrepsirrhini (suborder)UQ_con
EHMIPLemuriformes (infraorder)UQ_con
7HHZ6Opisthokonta (clade)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23],U4/U6.U5 tri-snRNP component SNU23,ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
9FSCSVertebrata (clade)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
H5SSSBilateria (clade)ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: