Domains within Homo sapiens protein I3L3H0_HUMAN (I3L3H0)

Phosphatidylcholine transfer protein

Alternative representations: 1 /

Protein length219 aa
Source databaseUniProt
Identifiers I3L3H0_HUMAN, I3L3H0, ENSP00000460437.1, ENSP00000460437
Source gene ENSG00000141179
Alternative splicing PPCT_HUMAN, I3L2M9_HUMAN, I3L3H0_HUMAN, J3QT99_HUMAN, ENSP00000325181.5, I3L4Z8_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

I3L3H0_HUMAN is shown as PCTP in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PCTP

Protein I3L3H0_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04927Cortisol synthesis and secretion

KEGG orthologous groups

KONameDescription
K24142STARD10StAR-related lipid transfer protein 10

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000460437 in eggNOG.

OGTaxonomic classDescription
LKOG2761All organisms (root)StAR-related lipid transfer protein 10,StAR-related lipid transfer protein 7, mitochondrial,steroidogenic acute regulatory protein, mitochondrial
KOG2761Eukaryota (superkingdom)StAR-related lipid transfer protein 10,StAR-related lipid transfer protein 7, mitochondrial,steroidogenic acute regulatory protein, mitochondrial
HUX4JMetazoa (kingdom)START
93MKMChordata (phylum)START
5QEJFSarcopterygii (superclass)START
8ZFF7Mammalia (class)START
4R63XEuarchontoglires (superorder)START
4ZUK0Primates (order)START
98S2NHaplorrhini (suborder)START
BV40CSimiiformes (infraorder)START
9EQVQCatarrhini (parvorder)START
9FHQJVertebrata (clade)START
7JS19Opisthokonta (clade)START
H50X2Bilateria (clade)START
FXE29Hominoidea (superfamily)START
5MZJ5Hominidae (family)START
5XXP5Homininae (subfamily)START

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: