Domains within Homo sapiens protein K7ES33_HUMAN (K7ES33)

Flt3-interacting zinc finger protein 1

Alternative representations: 1 /

Protein length68 aa
Source databaseUniProt
Identifiers K7ES33_HUMAN, K7ES33, ENSP00000468529.1, ENSP00000468529, A0A2I2ZSA0_GORGO, A0A2I2ZSA0, A0A2J8IWP8_PANTR, A0A2J8IWP8
Source gene ENSG00000179943
Alternative splicing FIZ1_HUMAN, ENSP00000465131.1, K7ES33_HUMAN, K7ERP0_HUMAN, K7EQX6_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

K7ES33_HUMAN is shown as FIZ1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for FIZ1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9593.ENSGGOP00000050017 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HW1H3Metazoa (kingdom)zf-C2H2,zf-C2H2_6,zf-met
94D2SChordata (phylum)zf-C2H2,zf-C2H2_6,zf-met
5R1HISarcopterygii (superclass)zf-C2H2,zf-C2H2_6,zf-met
8Z4MFMammalia (class)zf-C2H2,zf-C2H2_6
4R5XREuarchontoglires (superorder)zf-C2H2,zf-C2H2_6
4ZN85Primates (order)zf-C2H2,zf-C2H2_6
98BB7Haplorrhini (suborder)zf-C2H2,zf-C2H2_6
BV6TJSimiiformes (infraorder)zf-C2H2,zf-C2H2_6
9EUVCCatarrhini (parvorder)zf-C2H2,zf-C2H2_6
7H0IWOpisthokonta (clade)zf-C2H2,zf-C2H2_6,zf-met
9FJ74Vertebrata (clade)zf-C2H2,zf-C2H2_6,zf-met
H3SS6Bilateria (clade)zf-C2H2,zf-C2H2_6,zf-met
FX9UVHominoidea (superfamily)zf-C2H2,zf-C2H2_6
5N4FGHominidae (family)zf-C2H2
5XW6AHomininae (subfamily)zf-C2H2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: