Domains within Mus musculus protein KAP0_MOUSE (Q9DBC7)

cAMP-dependent protein kinase type I-alpha regulatory subunit

Alternative representations: 1 /

Protein length381 aa
Source databaseUniProt
Identifiers KAP0_MOUSE, Q9DBC7, ENSMUSP00000102288.1, ENSMUSP00000102288, ENSMUSP00000056500.6, ENSMUSP00000056500, Q3UKU7, Q9JHR5, Q9JHR6, Q3TYK4_MOUSE, Q3TYK4, Q6LCA5_RAT, Q6LCA5, F8S0Y0_MOUSE, F8S0Y0, Q3UBA7_MOUSE, Q3UBA7
Source gene ENSMUSG00000020612
Alternative splicing KAP0_MOUSE, A2AI69_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

KAP0_MOUSE is shown as Prkar1a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Prkar1a

Protein KAP0_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map04910Insulin signaling pathway

KEGG orthologous groups

KONameDescription
K10914crpCRP/FNR family transcriptional regulator, cyclic AMP receptor protein
K04739PRKARcAMP-dependent protein kinase regulator

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000102288 in eggNOG.

OGTaxonomic classDescription
LCOG0664All organisms (root)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, anaerobic regulatory protein,cAMP-dependent protein kinase regulator
KOG1113Eukaryota (superkingdom)cAMP-dependent protein kinase regulator,golgin subfamily B member 1,STE20-related kinase adapter protein beta
HVG4PMetazoa (kingdom)cAMP-dependent protein kinase regulator
94S8AChordata (phylum)cAMP-dependent protein kinase regulator
5R83FSarcopterygii (superclass)cAMP-dependent protein kinase regulator
8ZB3DMammalia (class)cAMP-dependent protein kinase regulator
4REMWEuarchontoglires (superorder)cAMP-dependent protein kinase regulator
AI8NVRodentia (order)cAMP-dependent protein kinase regulator
8DNDYMyomorpha (suborder)cAMP-dependent protein kinase regulator
H5J18Bilateria (clade)cAMP-dependent protein kinase regulator
7M5I1Opisthokonta (clade)cAMP-dependent protein kinase regulator
9FCFCVertebrata (clade)cAMP-dependent protein kinase regulator
CQ4IVMuridae (family)cAMP-dependent protein kinase regulator
AE4N7Murinae (subfamily)cAMP-dependent protein kinase regulator
5PWSFMus (genus)cAMP-dependent protein kinase regulator
HEF5VMus (subgenus)cAMP-dependent protein kinase regulator

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: