Domains within Homo sapiens protein KIF23_HUMAN (Q02241)

Kinesin-like protein KIF23

Alternative representations: 1 /

Protein length960 aa
Source databaseUniProt
Identifiers KIF23_HUMAN, Q02241, ENSP00000260363.4, ENSP00000260363, B4E1K0, Q8WVP0
Source gene ENSG00000137807
Alternative splicing KIF23_HUMAN, ENSP00000494167.1, H7BYN4_HUMAN, Q02241-2, H0YMJ4_HUMAN, H0YME6_HUMAN, ENSP00000453386.2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

KIF23_HUMAN is shown as KIF23 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for KIF23

Protein KIF23_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05206MicroRNAs in cancer

KEGG orthologous groups

KONameDescription
K10402KIF20kinesin family member 20
K17387KIF23kinesin family member 23

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 70 PTMs annotated in this protein:

PTMCount
Phosphorylation46
Ubiquitination20
Acetylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein KIF23.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000260363 in eggNOG.

OGTaxonomic classDescription
LKOG0247All organisms (root)kinesin family member 20,kinesin family member 23,kinesin family member 7
KOG0247Eukaryota (superkingdom)kinesin family member 20,kinesin family member 23,kinesin family member 7
HUD4KMetazoa (kingdom)kinesin family member 23,maestro heat-like repeat-containing protein family member 1
940YBChordata (phylum)kinesin family member 23
5QUI2Sarcopterygii (superclass)kinesin family member 23
8Z2VKMammalia (class)kinesin family member 23
4RII9Euarchontoglires (superorder)kinesin family member 23
501IXPrimates (order)kinesin family member 23
98AU9Haplorrhini (suborder)kinesin family member 23
BVF75Simiiformes (infraorder)kinesin family member 23
9EKPICatarrhini (parvorder)kinesin family member 23
H5QDYBilateria (clade)kinesin family member 23,maestro heat-like repeat-containing protein family member 1
7GMXWOpisthokonta (clade)kinesin family member 20,kinesin family member 23,maestro heat-like repeat-containing protein family member 1
9G2V6Vertebrata (clade)kinesin family member 23
FX0MGHominoidea (superfamily)kinesin family member 23
5MYXRHominidae (family)kinesin family member 23
5XWPTHomininae (subfamily)kinesin family member 23

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: