Domains within Rattus norvegicus protein MAG_RAT (P07722)

Myelin-associated glycoprotein

Alternative representations: 1 /

Protein length626 aa
Source databaseUniProt
Identifiers MAG_RAT, P07722, ENSRNOP00000028544.2, ENSRNOP00000028544, P02685, P07723
Source gene ENSRNOG00000021023
Alternative splicing MAG_RAT, G3V9B3_RAT

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

MAG_RAT is shown as Mag in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Mag

Protein MAG_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K06771MAG, GMA, SIGLEC4myelin associated glycoprotein
K17341HMCNhemicentin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 17 PTMs annotated in this protein:

PTMCount
Phosphorylation9
N-linked glycosylation7
Palmitoylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Mag.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000028544 in eggNOG.

OGTaxonomic classDescription
6XGBWAll organisms (root)hemicentin,CD22 antigen,PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
KOG4475Eukaryota (superkingdom)hemicentin,CD22 antigen,PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
HT0KJMetazoa (kingdom)myelin associated glycoprotein,sialic acid binding Ig-like lectin 5,CD22 antigen
93UD5Chordata (phylum)myelin associated glycoprotein,sialic acid binding Ig-like lectin 5,CD22 antigen
5R23PSarcopterygii (superclass)myelin associated glycoprotein
8ZM0JMammalia (class)myelin associated glycoprotein
4RQ12Euarchontoglires (superorder)myelin associated glycoprotein
AIF74Rodentia (order)myelin associated glycoprotein
8D8EQMyomorpha (suborder)myelin associated glycoprotein
9GQJCVertebrata (clade)myelin associated glycoprotein,sialic acid binding Ig-like lectin 5,CD22 antigen
H6NM3Bilateria (clade)myelin associated glycoprotein,sialic acid binding Ig-like lectin 5,CD22 antigen
7N50XOpisthokonta (clade)myelin associated glycoprotein,sialic acid binding Ig-like lectin 5,CD22 antigen
CQ9I3Muridae (family)myelin associated glycoprotein
AEC4KMurinae (subfamily)myelin associated glycoprotein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: