Domains within Homo sapiens protein MDM2_HUMAN (Q00987)

E3 ubiquitin-protein ligase Mdm2

Alternative representations: 1 /

Protein length491 aa
Source databaseUniProt
Identifiers MDM2_HUMAN, Q00987, ENSP00000444430.2, ENSP00000444430, A6NL51, A8K2S6, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q8WYJ1, Q8WYJ2, Q9UGI3, Q9UMT8, Q00987-11, A8WFP2_HUMAN, A8WFP2
Source gene ENSG00000135679
Alternative splicing ENSP00000258149.6, J3QST1_HUMAN, Q8NDW1_HUMAN, G3XA89_HUMAN, MDM2_HUMAN, ENSP00000377067.3, ENSP00000427828.1, ENSP00000439238.1, ENSP00000377068.2, F5GWH7_HUMAN, Q9H4C5_HUMAN, Q96DS5_HUMAN, Q00987-5, E5RJQ0_HUMAN, Q00987-2, Q9H4C3_HUMAN, F5GZB0_HUMAN, ENSP00000445222.1, F5H4Q8_HUMAN, F5GZC3_HUMAN, Q00987-4, J3KN53_HUMAN, ENSP00000335096.3, E5RHE2_HUMAN, Q8TE47_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: