Domains within Mus musculus protein NDUV1_MOUSE (Q91YT0)

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

Alternative representations: 1 /

Protein length464 aa
Source databaseUniProt
Identifiers NDUV1_MOUSE, Q91YT0, ENSMUSP00000042967.7, ENSMUSP00000042967, D3Z1U9_MOUSE, D3Z1U9, D3Z0K1_MOUSE, D3Z0K1, D3YXX5_MOUSE, D3YXX5
Source gene ENSMUSG00000037916
Alternative splicing ENSMUSP00000121915.1, NDUV1_MOUSE, D3YUM1_MOUSE, ENSMUSP00000120223.1, D6RG60_MOUSE, ENSMUSP00000123680.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

NDUV1_MOUSE is shown as Ndufv1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ndufv1

Protein NDUV1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04714Thermogenesis

KEGG orthologous groups

KONameDescription
K00335nuoFNADH-quinone oxidoreductase subunit F [EC:7.1.1.2] iPath3
K03942NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2] iPath3
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 11 PTMs annotated in this protein:

PTMCount
Nitrosylation6
Acetylation5

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Ndufv1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000042967 in eggNOG.

OGTaxonomic classDescription
LCOG1894All organisms (root)NADH-quinone oxidoreductase subunit F [EC:7.1.1.2],NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2],formate dehydrogenase iron-sulfur subunit
KOG2658Eukaryota (superkingdom)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2],gamma-aminobutyric acid type B receptor
HU0W6Metazoa (kingdom)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2],gamma-aminobutyric acid type B receptor
94407Chordata (phylum)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
5QS78Sarcopterygii (superclass)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
8ZHZ5Mammalia (class)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
4RGK2Euarchontoglires (superorder)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
AI4VWRodentia (order)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
8D8AGMyomorpha (suborder)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
H72JCBilateria (clade)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2],gamma-aminobutyric acid type B receptor
7MSHZOpisthokonta (clade)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2],gamma-aminobutyric acid type B receptor
9GEA5Vertebrata (clade)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
CPZX9Muridae (family)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
AE6U9Murinae (subfamily)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
5PU5SMus (genus)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
HDZC7Mus (subgenus)NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: