Domains within Mus musculus protein NOTO_MOUSE (Q5TIS6)

Homeobox protein notochord

Alternative representations: 1 /

Protein length240 aa
Source databaseUniProt
Identifiers NOTO_MOUSE, Q5TIS6, ENSMUSP00000087006.6, ENSMUSP00000087006
Source gene ENSMUSG00000068302
Alternative splicing NOTO_MOUSE, G3UZB3_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

NOTO_MOUSE is shown as Noto in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Noto

Protein NOTO_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05205Proteoglycans in cancer

KEGG orthologous groups

KONameDescription
K09317EMXhomeobox protein EMX

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000087006 in eggNOG.

OGTaxonomic classDescription
LKOG0843All organisms (root)homeobox protein EMX,homeobox protein notochord,homeobox protein ventral anterior
KOG0843Eukaryota (superkingdom)homeobox protein EMX,homeobox protein notochord,homeobox protein ventral anterior
HVEGUMetazoa (kingdom)homeobox protein notochord,homeobox protein DBX,homeobox protein MOX
940EYChordata (phylum)homeobox protein notochord
5QZQVSarcopterygii (superclass)homeobox protein notochord
8ZDP3Mammalia (class)homeobox protein notochord
4RR7XEuarchontoglires (superorder)homeobox protein notochord
AI39CRodentia (order)homeobox protein notochord
8DNANMyomorpha (suborder)homeobox protein notochord
7IMIDOpisthokonta (clade)homeobox protein notochord,homeobox protein DBX,homeobox protein MOX
H6HN0Bilateria (clade)homeobox protein notochord,homeobox protein DBX
9FC8WVertebrata (clade)homeobox protein notochord
CQ7FJMuridae (family)homeobox protein notochord
ADXTFMurinae (subfamily)homeobox protein notochord
5PI84Mus (genus)homeobox protein notochord
HEBVKMus (subgenus)homeobox protein notochord

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: