Domains within Homo sapiens protein O43464-2

Isoform 2 of Serine protease HTRA2, mitochondrial

Alternative representations: 1 /

Protein length361 aa
Source databaseUniProt
Identifiers O43464-2, ENSP00000312893.3, ENSP00000312893
Source gene ENSG00000115317
Alternative splicing HTRA2_HUMAN, O43464-2, ENSP00000399166.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: