Domains within Drosophila melanogaster protein P29774-2

Isoform B of DNA-binding protein D-ETS-3

Alternative representations: 1 /

Protein length257 aa
Source databaseUniProt
Identifiers P29774-2, FBPP0076763, B4QJ96_DROSI, B4QJ96, B4PJD0_DROYA, B4PJD0, B3NGD4_DROER, B3NGD4, A0A1W4V9G6_DROFC, A0A1W4V9G6
Source gene FBgn0005658
Alternative splicing FBpp0312432, FBpp0271863, FBpp0312433, P29774-2, ETS3_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

P29774-2 is shown as DsimGD13937 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DsimGD13937

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7240.B4QJ96 in eggNOG.

OGTaxonomic classDescription
FV0IXmelanogaster group (species group)friend leukemia integration 1 transcription factor
EIR0DEndopterygota (cohort)ETS-type family, other,friend leukemia integration 1 transcription factor,ETS oncogene family protein FEV
LKOG3806All organisms (root)friend leukemia integration 1 transcription factor,C-ets-1,GA-binding protein transcription factor, alpha
KOG3806Eukaryota (superkingdom)friend leukemia integration 1 transcription factor,C-ets-1,GA-binding protein transcription factor, alpha
HTG4BMetazoa (kingdom)friend leukemia integration 1 transcription factor,transcriptional regulator ERG,ETS-type family, other
HITA6Arthropoda (phylum)friend leukemia integration 1 transcription factor,ETS-type family, other,ETS oncogene family protein FEV
85CSPHexapoda (subphylum)ETS-type family, other,friend leukemia integration 1 transcription factor,ETS oncogene family protein FEV
AGRC9Neoptera (infraclass)ETS-type family, other,friend leukemia integration 1 transcription factor,ETS oncogene family protein FEV
ANCHUDiptera (order)friend leukemia integration 1 transcription factor,ETS-type family, other
7H4J0Opisthokonta (clade)friend leukemia integration 1 transcription factor,transcriptional regulator ERG,ETS-type family, other
H4BA0Bilateria (clade)friend leukemia integration 1 transcription factor,transcriptional regulator ERG,ETS-type family, other
EGVFJDrosophila (genus)friend leukemia integration 1 transcription factor
50DCMSophophora (subgenus)friend leukemia integration 1 transcription factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: