Domains within Homo sapiens protein P55290-4

Isoform 4 of Cadherin-13

Alternative representations: 1 /

Protein length760 aa
Source databaseUniProt
Identifiers P55290-4, ENSP00000268613.10, ENSP00000268613
Source gene ENSG00000140945
Alternative splicing CAD13_HUMAN, P55290-4, H3BV21_HUMAN, H3BQH4_HUMAN, H3BTF2_HUMAN, ENSP00000456491.1, ENSP00000408632.3, ENSP00000394557.3, F5H7W7_HUMAN, H3BRL7_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

P55290-4 is shown as CDH13 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CDH13

Protein P55290-4 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K16499PCDHD2protocadherin delta 2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000268613 in eggNOG.

OGTaxonomic classDescription
LKOG3594All organisms (root)protocadherin delta 2,protocadherin delta 1,protocadherin beta
KOG3594Eukaryota (superkingdom)protocadherin delta 2,protocadherin delta 1,protocadherin beta
HT1B0Metazoa (kingdom)cadherin 13, H-cadherin
94JB5Chordata (phylum)cadherin 13, H-cadherin
5R577Sarcopterygii (superclass)cadherin 13, H-cadherin
8Z2HZMammalia (class)cadherin 13, H-cadherin
4RHZ5Euarchontoglires (superorder)cadherin 13, H-cadherin
4ZS5ZPrimates (order)cadherin 13, H-cadherin
98FSZHaplorrhini (suborder)cadherin 13, H-cadherin
BVFMSSimiiformes (infraorder)cadherin 13, H-cadherin
9EST5Catarrhini (parvorder)cadherin 13, H-cadherin
H5DQDBilateria (clade)cadherin 13, H-cadherin
7JMM1Opisthokonta (clade)cadherin 13, H-cadherin
9FMJIVertebrata (clade)cadherin 13, H-cadherin
FXATSHominoidea (superfamily)cadherin 13, H-cadherin
5MY0EHominidae (family)cadherin 13, H-cadherin
5Y8D0Homininae (subfamily)cadherin 13, H-cadherin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: