Domains within Homo sapiens protein PAX2_HUMAN (Q02962)

Paired box protein Pax-2

Alternative representations: 1 /

Protein length417 aa
Source databaseUniProt
Identifiers PAX2_HUMAN, Q02962, ENSP00000396259.1, ENSP00000396259, Q15110, Q15837, Q5SZP2, Q5SZP3, Q15105, A0A2I3TPA8_PANTR, A0A2I3TPA8, F7HRH6_MACMU, F7HRH6, F7H7C8_CALJA, F7H7C8, F1MNR2_BOVIN, F1MNR2, A0A2K5WX52_MACFA, A0A2K5WX52, A0A2J8XY69_PONAB, A0A2J8XY69, A0A2K6EBG9_MACNE, A0A2K6EBG9, A0A2K5NCI4_CERAT, A0A2K5NCI4, A0A2K6Q8S0_RHIRO, A0A2K6Q8S0, A0A2I3LDG0_PAPAN, A0A2I3LDG0, A0A2K5S539_CEBCA, A0A2K5S539
Source gene ENSG00000075891
Alternative splicing ENSP00000347385.2, ENSP00000359319.3, A0A0A0MRH7_HUMAN, Q5SZP1_HUMAN, ENSP00000452489.2, PAX2_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

PAX2_HUMAN is shown as PAX2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PAX2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9541.ENSMFAP00000041693 in eggNOG.

OGTaxonomic classDescription
LKOG3862All organisms (root)paired box protein 2,paired box protein 5,paired box protein 8
KOG3862Eukaryota (superkingdom)paired box protein 2,paired box protein 5,paired box protein 8
HUIF1Metazoa (kingdom)paired box protein 2,paired box protein 5,paired box protein 8
94R3XChordata (phylum)paired box protein 2,paired box protein 5,paired box protein 8
5R0J0Sarcopterygii (superclass)paired box protein 2,paired box protein 5
8Z5CEMammalia (class)paired box protein 2,paired box protein 5
4R5D5Euarchontoglires (superorder)paired box protein 2
4ZSFNPrimates (order)paired box protein 2
98MUVHaplorrhini (suborder)paired box protein 2
BV6S9Simiiformes (infraorder)paired box protein 2
9EHHZCatarrhini (parvorder)paired box protein 2
7HBUAOpisthokonta (clade)paired box protein 2,paired box protein 5,paired box protein 8
H5K45Bilateria (clade)paired box protein 2,paired box protein 5,paired box protein 8
9GCG9Vertebrata (clade)paired box protein 2,paired box protein 5,paired box protein 8
6I3JBCercopithecidae (family)paired box protein 2
BRBT5Cercopithecinae (subfamily)paired box protein 2
53BQKMacaca (genus)paired box protein 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: