Domains within Homo sapiens protein Q06609-4

Isoform 4 of DNA repair protein RAD51 homolog 1

Alternative representations: 1 /

Protein length340 aa
Source databaseUniProt
Identifiers Q06609-4, ENSP00000433924.1, ENSP00000433924, ENSP00000372088.3, ENSP00000372088
Source gene ENSG00000051180
Alternative splicing ENSP00000432759.1, RAD51_HUMAN, ENSP00000454176.1, Q06609-4, E9PJ30_HUMAN, ENSP00000431897.1, E9PI54_HUMAN, H0YD61_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q06609-4 is shown as RAD51 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RAD51

Protein Q06609-4 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05212Pancreatic cancer
map03440Homologous recombination

KEGG orthologous groups

KONameDescription
K03553recArecombination protein RecA
K04482RAD51DNA repair protein RAD51

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000493712 in eggNOG.

OGTaxonomic classDescription
LCOG0468All organisms (root)recombination protein RecA,DNA repair protein RAD51,DNA repair protein RadA
KOG1433Eukaryota (superkingdom)DNA repair protein RAD51,RAD51-like protein 3,RAD51-like protein 1
HSPKFMetazoa (kingdom)DNA repair protein RAD51
94WMCChordata (phylum)DNA repair protein RAD51
5QJSTSarcopterygii (superclass)DNA repair protein RAD51
8YZJGMammalia (class)DNA repair protein RAD51
4RMJ6Euarchontoglires (superorder)DNA repair protein RAD51
4ZMMVPrimates (order)DNA repair protein RAD51
98D1BHaplorrhini (suborder)DNA repair protein RAD51
BV2J9Simiiformes (infraorder)DNA repair protein RAD51
9EFYUCatarrhini (parvorder)DNA repair protein RAD51
7HQ49Opisthokonta (clade)DNA repair protein RAD51
H4C9HBilateria (clade)DNA repair protein RAD51
9FZUIVertebrata (clade)DNA repair protein RAD51
FX797Hominoidea (superfamily)DNA repair protein RAD51
5MYBJHominidae (family)DNA repair protein RAD51
5Y8VJHomininae (subfamily)HHH_5,Rad51

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: