Domains within Homo sapiens protein Q32MH5-3

Isoform 3 of Protein FAM214A

Alternative representations: 1 /

Protein length1083 aa
Source databaseUniProt
Identifiers Q32MH5-3, ENSP00000443598.2, ENSP00000443598, H0Y3Q9_HUMAN, H0Y3Q9
Source gene ENSG00000047346
Alternative splicing F214A_HUMAN, Q32MH5-2, Q32MH5-3, H3BVB3_HUMAN, ENSP00000382153.4, H3BNT9_HUMAN, ENSP00000457666.1, ENSP00000455578.1, ENSP00000457402.1, ENSP00000457120.1, H3BSJ2_HUMAN, A0A087WV94_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

Q32MH5-3 is shown as FAM214A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for FAM214A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000443598 in eggNOG.

OGTaxonomic classDescription
LKOG2306All organisms (root)Chromosome_seg,DUF4210,ATG13
KOG2306Eukaryota (superkingdom)Chromosome_seg,DUF4210,ATG13
HTB9TMetazoa (kingdom)Chromosome_seg,DUF4210,PA28_alpha
93WI6Chordata (phylum)DUF4210,Chromosome_seg
5QDEDSarcopterygii (superclass)DUF4210,Chromosome_seg
8Z63AMammalia (class)DUF4210,Chromosome_seg
4RR8EEuarchontoglires (superorder)DUF4210,Chromosome_seg
4ZPFMPrimates (order)DUF4210,Chromosome_seg
986MSHaplorrhini (suborder)DUF4210,Chromosome_seg
BVG4SSimiiformes (infraorder)DUF4210,Chromosome_seg
9F03QCatarrhini (parvorder)DUF4210,Chromosome_seg
7NT87Opisthokonta (clade)DUF4210,Chromosome_seg,ATG13
9FS1KVertebrata (clade)DUF4210,Chromosome_seg
H6BEZBilateria (clade)Chromosome_seg,DUF4210,PA28_alpha
FX3W0Hominoidea (superfamily)DUF4210,Chromosome_seg
5N1Y2Hominidae (family)Chromosome_seg,DUF4210
5Y20BHomininae (subfamily)Chromosome_seg,DUF4210

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: