Domains within Mus musculus protein Q3UDC3_MOUSE (Q3UDC3)

Target of Myb protein 1

Alternative representations: 1 /

Protein length516 aa
Source databaseUniProt
Identifiers Q3UDC3_MOUSE, Q3UDC3, ENSMUSP00000077891.5, ENSMUSP00000077891, A0A1D5RM51_MOUSE, A0A1D5RM51, A0A1D5RL90_MOUSE, A0A1D5RL90, A0A1D5RM45_MOUSE, A0A1D5RM45
Source gene ENSMUSG00000042870
Alternative splicing TOM1_MOUSE, ENSMUSP00000148622.1, A0A1D5RM12_MOUSE, ENSMUSP00000148271.1, A0A1D5RM84_MOUSE, Q3UDC3_MOUSE, ENSMUSP00000148629.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q3UDC3_MOUSE is shown as Tom1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Tom1

Protein Q3UDC3_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04142Lysosome

KEGG orthologous groups

KONameDescription
K12404GGAADP-ribosylation factor-binding protein GGA

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 26 PTMs annotated in this protein:

PTMCount
Phosphorylation17
Ubiquitination8
Caspase cleavage aspartic acid1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Tom1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000077891 in eggNOG.

OGTaxonomic classDescription
LKOG1087All organisms (root)ADP-ribosylation factor-binding protein GGA,LAS seventeen-binding protein 5,beta-N-acetylhexosaminidase [EC:3.2.1.52]
KOG1087Eukaryota (superkingdom)ADP-ribosylation factor-binding protein GGA,LAS seventeen-binding protein 5,beta-N-acetylhexosaminidase [EC:3.2.1.52]
HUXKVMetazoa (kingdom)VHS,GAT,DUF4171
94BN7Chordata (phylum)VHS,GAT,DUF4171
5R8ZVSarcopterygii (superclass)VHS,GAT,DUF4171
8ZGNFMammalia (class)VHS,GAT
4REG2Euarchontoglires (superorder)VHS,GAT
AHXVBRodentia (order)VHS,GAT
8D8V9Myomorpha (suborder)VHS,GAT
H6CJ8Bilateria (clade)VHS,GAT,DUF4171
9G6ZQVertebrata (clade)VHS,GAT,DUF4171
7KDIYOpisthokonta (clade)VHS,GAT,DUF4171
CQ2G4Muridae (family)VHS,GAT
AE397Murinae (subfamily)VHS,GAT
5PP7NMus (genus)VHS,GAT
HE6B3Mus (subgenus)VHS,GAT

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: