Domains within Homo sapiens protein Q5QGZ9-1
Isoform 1 of C-type lectin domain family 12 member A
Alternative representations: 1 /
| Protein length | 275 aa |
|---|---|
| Source database | UniProt |
| Identifiers | Q5QGZ9-1, ENSP00000347916.4, ENSP00000347916 |
| Source gene | ENSG00000172322 |
| Alternative splicing | Q5QGZ9-1, ENSP00000379764.3, CL12A_HUMAN, ENSP00000405244.2, Q5QGZ9-4 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
This domain architecture was probably invented with the emergence of cellular organisms
Predicted functional partners
Q5QGZ9-1 is shown as 
CLEC12A in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein Q5QGZ9-1 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000347916 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LKOG4297 | All organisms (root) | mannose receptor, C type,CUB and sushi domain-containing protein,E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27] |
| KOG4297 | Eukaryota (superkingdom) | mannose receptor, C type,CUB and sushi domain-containing protein,E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27] |
| HVHZ4 | Metazoa (kingdom) | mannose receptor, C type,regenerating islet-derived protein 4,8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] |
| 94W6G | Chordata (phylum) | mannose receptor, C type,C-type lectin domain family 4 member M,collectin sub-family member 12 |
| 5R8XI | Sarcopterygii (superclass) | killer cell lectin-like receptor subfamily F member 1,killer cell lectin-like receptor subfamily B,C-type lectin domain family 12 member A |
| 8YWGZ | Mammalia (class) | C-type lectin domain family 12 member A |
| 4RPVC | Euarchontoglires (superorder) | C-type lectin domain family 12 member A |
| 4ZTTH | Primates (order) | C-type lectin domain family 12 member A |
| 98RWT | Haplorrhini (suborder) | C-type lectin domain family 12 member A |
| BV1P9 | Simiiformes (infraorder) | C-type lectin domain family 12 member A |
| 9EPHT | Catarrhini (parvorder) | C-type lectin domain family 12 member A |
| H4DS6 | Bilateria (clade) | mannose receptor, C type,regenerating islet-derived protein 4,C-type lectin domain family 4 member E |
| 7MCFY | Opisthokonta (clade) | mannose receptor, C type,regenerating islet-derived protein 4,8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] |
| 9FZ5E | Vertebrata (clade) | mannose receptor, C type,C-type lectin domain family 4 member M,collectin sub-family member 12 |
| FXF3W | Hominoidea (superfamily) | C-type lectin domain family 12 member A |
| 5NEKQ | Hominidae (family) | C-type lectin domain family 12 member A |
| 5Y7CY | Homininae (subfamily) | C-type lectin domain family 12 member A |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.