Domains within Mus musculus protein Q5STS9_MOUSE (Q5STS9)

B-cell lymphoma/leukemia 11A

Alternative representations: 1 /

Protein length835 aa
Source databaseUniProt
Identifiers Q5STS9_MOUSE, Q5STS9, ENSMUSP00000105140.1, ENSMUSP00000105140, Q9QYE3-15
Source gene ENSMUSG00000000861
Alternative splicing ENSMUSP00000112948.1, BC11A_MOUSE, ENSMUSP00000105142.1, Q5STS9_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q5STS9_MOUSE is shown as Bcl11a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Bcl11a

Protein Q5STS9_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05202Transcriptional misregulation in cancer
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein
K22045BCL11AB-cell lymphoma/leukemia 11A

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 57 PTMs annotated in this protein:

PTMCount
Phosphorylation47
Ubiquitination4
SUMOylation3
Acetylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Bcl11a.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000105140 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HUURRMetazoa (kingdom)B-cell lymphoma/leukemia 11B,B-cell lymphoma/leukemia 11A
93JMVChordata (phylum)B-cell lymphoma/leukemia 11B,B-cell lymphoma/leukemia 11A
5QZFMSarcopterygii (superclass)B-cell lymphoma/leukemia 11A
8YY6FMammalia (class)B-cell lymphoma/leukemia 11A
4RPF8Euarchontoglires (superorder)B-cell lymphoma/leukemia 11A
AHWVERodentia (order)B-cell lymphoma/leukemia 11A
8D8E0Myomorpha (suborder)B-cell lymphoma/leukemia 11A
9GUX6Vertebrata (clade)B-cell lymphoma/leukemia 11B,B-cell lymphoma/leukemia 11A
7N122Opisthokonta (clade)B-cell lymphoma/leukemia 11B,B-cell lymphoma/leukemia 11A
H4791Bilateria (clade)B-cell lymphoma/leukemia 11B,B-cell lymphoma/leukemia 11A
CQ8ZFMuridae (family)B-cell lymphoma/leukemia 11A
AE3VPMurinae (subfamily)B-cell lymphoma/leukemia 11A
5PY04Mus (genus)B-cell lymphoma/leukemia 11A
HE398Mus (subgenus)B-cell lymphoma/leukemia 11A

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: