Domains within Danio rerio protein Q6NZ01_DANRE (Q6NZ01)

Brain-derived neurotrophic factor

Alternative representations: 1 /

Protein length270 aa
Source databaseUniProt
Identifiers Q6NZ01_DANRE, Q6NZ01, ENSDARP00000152925.1, ENSDARP00000152925, ENSDARP00000108984.2, ENSDARP00000108984, ENSDARP00000010990.5, ENSDARP00000010990, C5IG38_DANRE, C5IG38, F1Q5K0_DANRE, F1Q5K0, B0V301_DANRE, B0V301
Source gene ENSDARG00000018817
Alternative splicing Q6NZ01_DANRE, ENSDARP00000114671.1, E9QIT5_DANRE, ENSDARP00000069872.3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Vertebrata

Predicted functional partners

Q6NZ01_DANRE is shown as bdnf in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for bdnf

Protein Q6NZ01_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05016Huntington disease

KEGG orthologous groups

KONameDescription
K04355BDNFbrain-derived neurotrophic factor

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000010990 in eggNOG.

OGTaxonomic classDescription
72T26All organisms (root)brain-derived neurotrophic factor
9IKPSOtomorpha (cohort)brain-derived neurotrophic factor
5EU61Eukaryota (superkingdom)brain-derived neurotrophic factor
HTAQ9Metazoa (kingdom)brain-derived neurotrophic factor
94WMKChordata (phylum)brain-derived neurotrophic factor
FXJ0EActinopterygii (superclass)brain-derived neurotrophic factor
8N5HINeopterygii (subclass)brain-derived neurotrophic factor
7I6V0Opisthokonta (clade)brain-derived neurotrophic factor
9G83ZVertebrata (clade)brain-derived neurotrophic factor
H40BJBilateria (clade)brain-derived neurotrophic factor
BEITMCyprinidae (family)brain-derived neurotrophic factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: