Domains within Homo sapiens protein Q6QNK2-4

Isoform 4 of Adhesion G-protein coupled receptor D1

Alternative representations: 1 /

Protein length906 aa
Source databaseUniProt
Identifiers Q6QNK2-4, ENSP00000444425.1, ENSP00000444425
Source gene ENSG00000111452
Alternative splicing AGRD1_HUMAN, F5H7I3_HUMAN, Q6QNK2-4, A0A087WYZ5_HUMAN, H0Y2U9_HUMAN, Q6QNK2-3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

Q6QNK2-4 is shown as ADGRD1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ADGRD1

Protein Q6QNK2-4 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03250Viral life cycle - HIV-1

KEGG orthologous groups

KONameDescription
K07936RANGTP-binding nuclear protein Ran

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000444425 in eggNOG.

OGTaxonomic classDescription
LKOG0096All organisms (root)GTP-binding nuclear protein Ran,adhesion G protein-coupled receptor B3,adhesion G-protein coupled receptor D1
KOG0096Eukaryota (superkingdom)GTP-binding nuclear protein Ran,adhesion G protein-coupled receptor B3,adhesion G-protein coupled receptor D1
HVXCFMetazoa (kingdom)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
9416CChordata (phylum)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
5R5ZNSarcopterygii (superclass)adhesion G-protein coupled receptor D1
8YW0WMammalia (class)adhesion G-protein coupled receptor D1
4RPCIEuarchontoglires (superorder)adhesion G-protein coupled receptor D1
4ZKW5Primates (order)adhesion G-protein coupled receptor D1
98C47Haplorrhini (suborder)adhesion G-protein coupled receptor D1
BUZANSimiiformes (infraorder)adhesion G-protein coupled receptor D1
9EMVKCatarrhini (parvorder)adhesion G-protein coupled receptor D1
H3YM4Bilateria (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
7H5M4Opisthokonta (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
9GUP4Vertebrata (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
FX5UQHominoidea (superfamily)adhesion G-protein coupled receptor D1
5N7CSHominidae (family)adhesion G-protein coupled receptor D1
5XVEAHomininae (subfamily)adhesion G-protein coupled receptor D1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: