Domains within Homo sapiens protein Q6UXI9-3

Isoform 3 of Nephronectin

Alternative representations: 1 /

Protein length595 aa
Source databaseUniProt
Identifiers Q6UXI9-3, ENSP00000389252.2, ENSP00000389252
Source gene ENSG00000168743
Alternative splicing D6RE63_HUMAN, NPNT_HUMAN, Q6UXI9-6, Q6UXI9-3, Q6UXI9-5, Q6UXI9-2, Q6UXI9-4, D6RH31_HUMAN, H0YAK9_HUMAN, H0Y8M1_HUMAN, H0YA60_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q6UXI9-3 is shown as NPNT in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NPNT

Protein Q6UXI9-3 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04512ECM-receptor interaction

KEGG orthologous groups

KONameDescription
K06824NPNTnephronectin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000389252 in eggNOG.

OGTaxonomic classDescription
746YWAll organisms (root)nephronectin
5JBU1Eukaryota (superkingdom)nephronectin
HSXBWMetazoa (kingdom)nephronectin
93PK8Chordata (phylum)nephronectin
5QG22Sarcopterygii (superclass)nephronectin
8Z0YZMammalia (class)nephronectin
4R60MEuarchontoglires (superorder)nephronectin
4ZRFYPrimates (order)nephronectin
98DZHHaplorrhini (suborder)nephronectin
BUYQPSimiiformes (infraorder)nephronectin
9EMY4Catarrhini (parvorder)nephronectin
9GTVAVertebrata (clade)nephronectin
H6X0CBilateria (clade)nephronectin
7NUTEOpisthokonta (clade)nephronectin
FWZ77Hominoidea (superfamily)nephronectin
5N1HSHominidae (family)nephronectin
5XSZEHomininae (subfamily)nephronectin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: