Domains within Danio rerio protein Q7T3G1_DANRE (Q7T3G1)

GATA-binding protein 2a

Alternative representations: 1 /

Protein length456 aa
Source databaseUniProt
Identifiers Q7T3G1, Q7T3G1_DANRE, ENSDARP00000076860.3, ENSDARP00000076860, F1QT93
Source gene ENSDARG00000059327
Alternative splicing ENSDARP00000076855.4, Q7T3G1_DANRE, A0A0R4IKY6_DANRE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q7T3G1_DANRE is shown as gata2a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for gata2a

Protein Q7T3G1_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04928Parathyroid hormone synthesis, secretion and action
map04075Plant hormone signal transduction

KEGG orthologous groups

KONameDescription
K17894GATA2GATA-binding protein 2
K14492ARR-Atwo-component response regulator ARR-A family

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 8 PTMs annotated in this protein:

PTMCount
Phosphorylation7
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein gata2a.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000076860 in eggNOG.

OGTaxonomic classDescription
LKOG1601All organisms (root)two-component response regulator ARR-A family,acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26],GATA-binding protein, other eukaryote
9IHN5Otomorpha (cohort)GATA-binding protein 2
KOG1601Eukaryota (superkingdom)two-component response regulator ARR-A family,acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26],GATA-binding protein, other eukaryote
HTSA8Metazoa (kingdom)GATA-binding protein 2,GATA-binding protein 3,GATA-binding protein 4
93YEFChordata (phylum)GATA-binding protein 2,GATA-binding protein 3
FY4IBActinopterygii (superclass)GATA-binding protein 2
8MZU5Neopterygii (subclass)GATA-binding protein 2
9FY1TVertebrata (clade)GATA-binding protein 2,GATA-binding protein 3
H3V08Bilateria (clade)GATA-binding protein 2,GATA-binding protein 3,GATA-binding protein 4
7JUJNOpisthokonta (clade)GATA-binding protein 2,GATA-binding protein 3,GATA-binding protein, other eukaryote
BETT2Cyprinidae (family)GATA-binding protein 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: