Domains within Mus musculus protein Q80YX1-2

Isoform 2 of Tenascin

Alternative representations: 1 /

Protein length2019 aa
Source databaseUniProt
Identifiers Q80YX1-2, ENSMUSP00000030056.5, ENSMUSP00000030056, ENSMUSP00000103000.3, ENSMUSP00000103000
Source gene ENSMUSG00000028364
Alternative splicing Q80YX1-2, TENA_MOUSE, Q80YX0_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

Q80YX1-2 is shown as Tnc in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Tnc

Protein Q80YX1-2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04510Focal adhesion
map04151PI3K-Akt signaling pathway

KEGG orthologous groups

KONameDescription
K06252TNtenascin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000103000 in eggNOG.

OGTaxonomic classDescription
LKOG2579All organisms (root)tenascin,ficolin,microfibrillar-associated protein 4
LKOG1225All organisms (root)tenascin,WNT inhibitory factor 1,teneurin
KOG1225Eukaryota (superkingdom)tenascin,WNT inhibitory factor 1,teneurin
KOG2579Eukaryota (superkingdom)tenascin,ficolin,microfibrillar-associated protein 4
HU9GJMetazoa (kingdom)tenascin,ficolin
94KBTChordata (phylum)tenascin
5RAEFSarcopterygii (superclass)tenascin
8YYJAMammalia (class)tenascin
4RJYEEuarchontoglires (superorder)tenascin
AI850Rodentia (order)tenascin
8DFVVMyomorpha (suborder)tenascin
7P1NWOpisthokonta (clade)tenascin,ficolin
9G5JHVertebrata (clade)tenascin
H6514Bilateria (clade)tenascin,ficolin
CQDS3Muridae (family)tenascin
ADYBHMurinae (subfamily)tenascin
5PF5NMus (genus)tenascin
HE98WMus (subgenus)tenascin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: