Domains within Mus musculus protein Q8VIM5-3

Isoform 3 of Myocardin

Alternative representations: 1 /

Protein length983 aa
Source databaseUniProt
Identifiers Q8VIM5-3, ENSMUSP00000104335.2, ENSMUSP00000104335
Source gene ENSMUSG00000020542
Alternative splicing MYCD_MOUSE, ENSMUSP00000098603.2, F6TBX6_MOUSE, Q8VIM5-3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

Q8VIM5-3 is shown as Myocd in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Myocd

Protein Q8VIM5-3 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04010MAPK signaling pathway

KEGG orthologous groups

KONameDescription
K04421MAP3K3, MEKK3mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000104335 in eggNOG.

OGTaxonomic classDescription
LKOG0198All organisms (root)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 17/18,MKL/myocardin-like protein
KOG0198Eukaryota (superkingdom)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 17/18,MKL/myocardin-like protein
HVECGMetazoa (kingdom)myocardin
93XMHChordata (phylum)myocardin
5QTJYSarcopterygii (superclass)myocardin
8YX4CMammalia (class)myocardin
4RFGHEuarchontoglires (superorder)myocardin
AIA50Rodentia (order)myocardin
8DHP3Myomorpha (suborder)myocardin
7GF1KOpisthokonta (clade)myocardin
H399JBilateria (clade)myocardin
9G49MVertebrata (clade)myocardin
CQ9F2Muridae (family)myocardin
AECZPMurinae (subfamily)myocardin
5PT54Mus (genus)myocardin
HE18TMus (subgenus)myocardin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: