Domains within Mus musculus protein Q9CS84-2

Isoform 2a of Neurexin-1

Alternative representations: 1 /

Protein length1507 aa
Source databaseUniProt
Identifiers Q9CS84-2, ENSMUSP00000125407.3, ENSMUSP00000125407
Source gene ENSMUSG00000024109
Alternative splicing Q9CS84-4, Q9CS84-2, Q9CS84-6, Q9CS84-5, E0CZA5_MOUSE, G3UWQ9_MOUSE, NRX1B_MOUSE, NRX1A_MOUSE, A0A140LI71_MOUSE, Q9CS84-3, A0A0H2UH29_MOUSE, E0CY11_MOUSE, A0A0G2JE40_MOUSE, A0A0G2JES8_MOUSE, ENSMUSP00000135241.1, H3BK93_MOUSE, A0A0G2JE65_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eutheria

Predicted functional partners

Q9CS84-2 is shown as Nrxn1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Nrxn1

Protein Q9CS84-2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K07377NRXNneurexin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000125407 in eggNOG.

OGTaxonomic classDescription
LKOG3514All organisms (root)neurexin
KOG3514Eukaryota (superkingdom)neurexin
HSME9Metazoa (kingdom)neurexin
94PJKChordata (phylum)neurexin
5QBSDSarcopterygii (superclass)neurexin
8ZI9EMammalia (class)neurexin
4R5WNEuarchontoglires (superorder)neurexin
AI3T5Rodentia (order)neurexin
8DCGGMyomorpha (suborder)neurexin
9GP1AVertebrata (clade)neurexin
7IPJDOpisthokonta (clade)neurexin
H52AUBilateria (clade)neurexin
CQ4HWMuridae (family)neurexin
ADY8GMurinae (subfamily)neurexin
5PSTXMus (genus)neurexin
HE3FWMus (subgenus)neurexin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: